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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKA
All Species:
33.33
Human Site:
Y212
Identified Species:
48.89
UniProt:
O14965
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14965
NP_003591.2
403
45809
Y212
R
V
Y
L
I
L
E
Y
A
P
L
G
T
V
Y
Chimpanzee
Pan troglodytes
XP_525364
403
45791
Y212
R
V
Y
L
I
L
E
Y
A
P
L
G
T
V
Y
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
F284
R
V
Y
L
I
L
E
F
A
P
R
G
E
L
Y
Dog
Lupus familis
XP_853397
405
45606
Y213
R
V
Y
L
I
L
E
Y
A
P
L
G
A
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
P97477
395
44754
Y203
R
V
Y
L
I
L
E
Y
A
P
L
G
T
V
Y
Rat
Rattus norvegicus
P59241
397
44856
Y205
R
V
Y
L
I
L
E
Y
A
P
L
G
T
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
R119
A
P
R
G
E
V
Y
R
E
L
Q
K
F
S
K
Chicken
Gallus gallus
XP_425725
409
46456
F214
I
L
R
L
Y
G
Y
F
H
D
V
T
R
V
Y
Frog
Xenopus laevis
Q91819
408
46443
Y219
R
V
Y
L
I
L
D
Y
A
P
G
G
E
L
F
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
G136
I
L
E
Y
A
P
R
G
E
M
Y
K
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
G144
E
L
F
K
H
L
R
G
A
P
N
H
R
F
D
Honey Bee
Apis mellifera
XP_395732
327
37711
Y143
R
I
Y
L
I
L
E
Y
A
P
N
G
E
L
F
Nematode Worm
Caenorhab. elegans
O01427
305
34731
V121
E
M
Y
K
Q
L
T
V
S
K
R
F
S
E
P
Sea Urchin
Strong. purpuratus
XP_001181990
278
32048
Y94
Y
A
P
R
G
E
L
Y
K
Q
L
Q
R
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
Y98
R
V
Y
L
I
L
E
Y
A
V
R
G
E
L
Y
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
Y183
R
V
Y
L
L
M
E
Y
L
V
N
G
E
M
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
47.7
89.8
N.A.
82.6
83.6
N.A.
65.5
73.1
65.9
53.3
N.A.
38.4
53
46.6
50.6
Protein Similarity:
100
100
62.2
93
N.A.
86.8
87.3
N.A.
70.2
82.8
77.2
65.7
N.A.
57.8
67
56.3
60
P-Site Identity:
100
100
73.3
93.3
N.A.
100
100
N.A.
0
20
66.6
0
N.A.
20
66.6
13.3
13.3
P-Site Similarity:
100
100
86.6
93.3
N.A.
100
100
N.A.
6.6
40
86.6
13.3
N.A.
33.3
86.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.3
57.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
0
63
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
7
% D
% Glu:
13
0
7
0
7
7
57
0
13
0
0
0
38
7
0
% E
% Phe:
0
0
7
0
0
0
0
13
0
0
0
7
7
7
13
% F
% Gly:
0
0
0
7
7
7
0
13
0
0
7
63
0
0
7
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
13
7
0
0
57
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
0
0
0
7
7
0
13
0
0
7
% K
% Leu:
0
19
0
69
7
69
7
0
7
7
38
0
0
32
0
% L
% Met:
0
7
0
0
0
7
0
0
0
7
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
7
7
0
0
7
0
0
0
57
0
0
0
0
7
% P
% Gln:
0
0
0
0
7
0
0
0
0
7
7
7
0
0
7
% Q
% Arg:
63
0
13
7
0
0
13
7
0
0
19
0
19
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
7
0
0
0
7
7
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
7
25
0
0
% T
% Val:
0
57
0
0
0
7
0
7
0
13
7
0
0
38
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
69
7
7
0
13
63
0
0
7
0
0
0
57
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _